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Unpasturized milk can be associated with a number of infections including Listeria monocytogenes, Campylobacter jejuni, Salmonella species, Brucella species, and Escherichia coli

Treatment of Brucella is with doxycycline and rifampin. In those less than eight years of age the treatment is TMP/SMX and rifampin. Gentimicin can be added for more serious cases.

Doxycycline with Streptomycin is not listed in the Redbook as the treatment regimen and Streptomycin has limited availability in the US however this regimen may be more effective and is used globally.


Committee on Infectious Diseases; Committee on Nutrition; American Academy of Pediatrics. Consumption of raw or unpasteurized milk and milk products by pregnant women and children. Pediatrics. 2014 Jan;133(1):175-9. PMID 24344105

American Academy of Pediatrics. Burcellosis. In: Kimberlin DW, Brady MT, Jackson MA, Long SS, eds. Red Book: 2018 Report of the Committee on Infectious Diseases. American Academy of Pediatrics; 2018;

Yousefi-Nooraie R, Mortaz-Hejri S, Mehrani M, Sadeghipour P. Antibiotics for treating human brucellosis. Cochrane Database Syst Rev. 2012 Oct 17;10:CD007179. PMID 23076931